The hemophilia takes one kind of hereditary disease, so far, does not have the permanent control means. But through increases patient’s hemoglutination factor active level, may eliminate patient’s symptom effectively. May through give the patient the infusion normal person’s blood plasma, increases the patient hemoglutination factor the active level, but a more effective method is, for the patient infusion concentration hemoglutination factor, this is called the hemoglutination factor therapy. However, cannot become effective the too long time by the infusion to patient blood vessel in hemoglutination factor, because each kind of hemoglutination factor has its half-life,?The factor half-life is from 8 to 12 hours,?The factor half-life is from 18 to 24 hours, thus the input blood plasma or the concentration hemoglutination factor’s therapy, can only eliminate the patient symptom temporarily.
If use for patient regular infusion concentration hemoglutination factor prevention therapy, even if is the specific weight hemophiliac, may also on nearly with the normal person same life, but because the concentration hemoglutination factor is very expensive, China’s patients are very difficult to withstand this prevention therapy, can only after having the hemorrhage the infusion concentration hemoglutination factor.
Because the concentration hemoglutination factor must withdraw from the massive blood plasmas, thus the hemoglutination factor therapy is very easy to disseminate the virus, in the history once had the massive hemophiliac to infect AIDS, hepatitis B, hepatitis C’s tragedy. in 1985 started to concentrate the hemoglutination factor to carry on heating processing, in 1987 has used the enhancement viral deactivation method, thus caused the concentration hemoglutination factor no longer to disseminate the virus. However, in China, in 1995 only then has not been forbidden after the viral fire fighting processing concentration hemoglutination factor to produce.
In recent years, countries and so on Canada started with the genetic engineering to produce more inexpensive and the safe concentration hemoglutination factor.